Do Glutamine Supplements Work?

Glutamine is well known in the fitness and bodybuilding community for its influence on preserving and building muscle mass. But it’s more than just a supplement for gym rats.

It’s also widely used to help treat many serious illnesses like cancer, HIV, and disorders of the immune system.

Here’s the most beneficial uses for glutamine supplements and how it works.

Glutamine For Muscle Mass

Your natural glutamine levels are dramatically decreased with every vigorous workout. It can take 4-6 days for these levels to return to normal, making supplementation beneficial to anyone who exercises regularly. Here’s how glutamine helps build and maintain muscle mass:


Glutamine is at the top of the supplement list for many bodybuilders and athletes. Glutamine may not be a rockstar for adding new muscle mass, but it does play a vital role in the preservation of existing muscle.

It can aid in catobolism (breaking down protein), and as a way to boost your immune system to fight off illness. Getting sick, and bedridden for weeks, is one of the fastest ways to lose hard earned muscle gains.

Growth Hormone

Glutamine plays a role in protein synthesis, preventing protein breakdown, and also influences your natural growth hormone levels. Studies have shown a significant increase in growth hormone secretion with as little as two grams of L-glutamine supplementation per day.

Growth hormone can help metabolize fat, prevent muscle loss, and increase new muscle mass.

See Also: How to boost testosterone naturally

Glutamine For Gut Health

Many common illnesses related to an auto immune disorder can be linked to your gut health, or the health or your intestinal wall. A leaky gut can allow bacteria, toxic waste, and food particles normally housed inside your intestinal wall to pass through causing numerous health problems.

Symptoms Of Poor Gut Health:

  • Bloating
  • Increased Fatigue
  • Weight Gain
  • Joint Pain
  • Digestive Problems
  • Food Sensitivities & Allergies
  • Thyroid Disorders

Supplementing with L-glutamine, to improve gut health, can act as an anti-inflammatory helping to repair the lining of your intestinal wall. If you’re having problems with gut health, you can see improvements with a daily supplementation of 2-5 grams of glutamine per day.

Related: How to intermittent fast for weight loss

Glutamine For Medical Treatments

In additions to gut health, glutamine is also commonly used to help treat the side effects of harmful cancer treatments. People undergoing chemotherapy or radiation therapy are often given glutamine to help with the following:

  • Diarrhea
  • Pain or swelling in the mouth
  • Joint pain
  • Muscle pain
  • Immune system boost

Other serious illnesses effecting the immune system are also treated with glutamine supplements.  Glutamine has also shown benefits in treating people with ADHD, urinary disorders, and sickle cell anemia.

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